Background and aim: Subjects with nonsyndromic cleft lip and/or palate (CLP) present high frequency of hypodontia, both inside and outside the cleft region, which may represent a complicating factor for the dental management. Our aim was to evaluate the prevalence of tooth agenesis in a large sample of cleft subjects and to evaluate the relation with gender, cleft type and sidedness.
Materials and methods: Tooth agenesis was identified from serial panoramic radiographs of 293 subjects (123 female, 170 male) with unilateral (66%), bilateral CLP (17%) and isolated cleft palate (17%). Association between tooth agenesis and the different variables was assessed by chi-square test and Poisson regression model (P