Currently, there is a decline in the discovery of new antibiotics. Several
important habitats that have yet to be fully exploited for antibioticproducing bacteria include water and the anterior nares. Therefore,
antibiotic-producing bacteria isolated from these two environments were
evaluated for antibiotic production, and using ribosome engineering, their
activity was further enhanced. Five NW Pseudomonas sp. strains isolated
from water were tested for antimicrobial activity against multidrug-resistant
bacteria. The five strains were grown under various conditions, by which
the growth medium significantly influenced the production of antimicrobials
(p-value