The dissertation belongs to the field of medical measurements. Its scope includes investigation of the additional biophysical biomarkers: lower than normal intracranial pressure and deteriorated cerebral blood flow autoregulation; and exploration of the potential for their inclusion into the diagnosis of glaucoma. The topic of additional biomarkers for glaucoma diagnosis is analyzed within the framework of the 4 published articles, from a holistic point of view, providing ideas and insights for the more precise diagnosis, (noninvasive) treatment of glaucoma and its risk management, in the conclusions.