Physical activity and cognitive vitality: Insights from the Rotterdam Study and an intervention study in healthy older adults - PhDData

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Physical activity and cognitive vitality: Insights from the Rotterdam Study and an intervention study in healthy older adults

The thesis was published by Galle, Sara, in March 2023, Erasmus University Rotterdam.

Abstract:

Physical inactivity is considered a promising intervention target to delay or prevent the development of accelerated cognitive decline and dementia. The main objective of this thesis was to investigate causality in the relation between physical activity and cognitive vitality. In addition, the potential moderating role of genetic susceptibility to Alzheimer’s disease, based on the APOE gene and the predicitve validity of neurotrophic factors IGF-I and BDNF is investigated.



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