Clinical aspects of non-severe hemophilia: Focus on bleeding, joint and treatment outcomes
The thesis was published by
Kloosterman, F.R.,
in January 2023,
University of Amsterdam.
Abstract:
Hemophilia A and B are rare inherited bleeding disorders, caused by mutations in the F8 or F9 gene on the X-chromosome leading to a deficiency of coagulation factor VIII (FVIII) or coagulation factor IX (FIX), respectively. As a result, persons with decreased coagulation FVIII/IX levels have an increased bleeding tendency. Classification of disease severity is based on the endogenous FVIII/IX level, ranging from severe (FVIII/IX
The full thesis can be downloaded at :
https://pure.uva.nl/ws/files/124605860/cover.jpg
https://pure.uva.nl/ws/files/124605862/Front_matter.pdf
https://pure.uva.nl/ws/files/124605864/Chapter_1.pdf
https://pure.uva.nl/ws/files/124605866/Chapter_2.pdf
https://pure.uva.nl/ws/files/124605868/Chapter_3.pdf
https://pure.uva.nl/ws/files/124605872/Chapter_5.pdf
https://pure.uva.nl/ws/files/124605874/Chapter_6.pdf
https://pure.uva.nl/ws/files/124605878/Chapter_8.pdf
https://pure.uva.nl/ws/files/124605880/Chapter_9.pdf
https://pure.uva.nl/ws/files/124605882/Chapter_10.pdf
https://pure.uva.nl/ws/files/124605884/Chapter_11.pdf
https://pure.uva.nl/ws/files/124605886/Appendices.pdf
https://dare.uva.nl/personal/pure/en/publications/clinical-aspects-of-nonsevere-hemophilia
https://pure.uva.nl/ws/files/124605860/cover.jpg
https://pure.uva.nl/ws/files/124605862/Front_matter.pdf
https://pure.uva.nl/ws/files/124605864/Chapter_1.pdf
https://pure.uva.nl/ws/files/124605866/Chapter_2.pdf
https://pure.uva.nl/ws/files/124605868/Chapter_3.pdf
https://pure.uva.nl/ws/files/124605872/Chapter_5.pdf
https://pure.uva.nl/ws/files/124605874/Chapter_6.pdf
https://pure.uva.nl/ws/files/124605878/Chapter_8.pdf
https://pure.uva.nl/ws/files/124605880/Chapter_9.pdf
https://pure.uva.nl/ws/files/124605882/Chapter_10.pdf
https://pure.uva.nl/ws/files/124605884/Chapter_11.pdf
https://pure.uva.nl/ws/files/124605886/Appendices.pdf
https://dare.uva.nl/personal/pure/en/publications/clinical-aspects-of-nonsevere-hemophilia