Mechanisms and nutritional countermeasures to musculoskeletal disuse atrophy - PhDData

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Mechanisms and nutritional countermeasures to musculoskeletal disuse atrophy

The thesis was published by Edwards, Sophie Jacqueline, in July 2022, University of Birmingham.

Abstract:

Musculoskeletal disuse negatively impacts muscle mass and physiological functioning. Mechanistically, disuse-induced alterations in muscle mass are underpinned by alterations in myofibrillar protein turnover. However, the implications of disuse on mitochondrial functioning remains to be fully eluded. Accordingly, Chapter 2 explored whether a 7d period of reduced ambulation (



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