Under current plans, the EU aims to be climateneutralby 2050. However, its industrial sector –which makes up nearly a quarter of its total energyconsumption – still faces significant technical andinstitutional barriers to decarbonization.This study uses Greece as a case study to investigatethe role of biomass and biomass-derived fuels inachieving a future carbon-neutral industrial sector inline with EU targets. This study uses IndustryPLANand a methodology which includes interviews and aliterature review to create different scenariosregarding the future industrial fuel mix in Greece.These scenarios specify the demand that can becovered by biomass fuels or electricity, dependingon the required process temperatures.The results of this investigation are integrated intothe EnergyPLAN, and the final evaluation of thefuture scenarios considers the remaining sections ofthe Greek energy system.The evaluation shows that high electrification alonedoes not reduce biomass consumption in contrast tohydrogen use; higher use of dry biomass leads tobetter economic results. The preferable scenarioinvestigated in this study is one that combineselectrification, dry biomass, and gaseous biomasscombustion. It is the preferable scenario because itoffers fuel flexibility and limits biomassconsumption and overall costs.In contrast, scenarios which use gaseouselectrofuels as an alternative to biomass candecrease biomass consumption but increase systemcosts.The study concludes that there are feasiblealternatives to decarbonize the Greek industrialsector while keeping biomass consumption at asustainable level.