3D genomics:: form and function of chromatin
The thesis was published by
van der Weide, Robin,
in March 2022,
Erasmus University Rotterdam.
Abstract:
DNA is stored in the nucleus of every cell in the same way, but how is this done? We show that the Cohesin-complex plays a major role in the formation and maintenance of chromatin-loops and that this affects multiple layers of gene-regulation.