Development of a novel scale-down method to study pH and dissolved oxygen heterogeneities in mammalian cell cultures
The thesis was published by
Zakrzewski, Roman,
in October 2022,
UCL (University College London).
Abstract:
In recent years, there has been a growing interest in studying the effects of spatial
heterogeneities that are present in large-scale cell culture bioreactors. When scaling up from
bench-top to production bioreactors mixing times often increase, which make heterogeneities
within large-scale vessels more likely.
The full thesis can be downloaded at :
https://discovery.ucl.ac.uk/id/eprint/10157903/2/Zakrzewski_10157903_Thesis.pdf
https://discovery.ucl.ac.uk/id/eprint/10157903/2/Zakrzewski_10157903_Thesis.pdf