Polysaccharides, caffeic acid derivatives, lipophilic alkylamides, various components of es-sential oil and other ingredients are stored in the roots of Echinacea purpurea (L.) Moench. In vivo and in vitro studies have shown that the accumulation of caffeic acid derivatives and poly-saccharides in the herbal plant drug is related to the immunomodulatory effects of Echinacea purpurea (L.) Moench. The hemagglutinating activity of Echinacea purpurea (L.) Moench ethanolic tincture was no-ticed previously. Despite that, a wider investigation of purple coneflower lectins hasn’t been done. There is no data on the qualitative and quantitative content of Echinacea puprurea (L.) Moench root lectins, as well as their impact on secondary immune response in mice. The aim of the study . To purify lectins from purple coneflower (Echinacea purpurea (L.) Moench roots, evaluate their quality, quantity and effect on immune system reactions in vivo. The objectives of the study: 1. To purify and quantify proteins from fresh purple coneflower (Echinacea purpurea (L.) Moench) roots. 2. To purify lectins from extracted proteins; 3. To evaluate purified lectins qualitatively; 4. To estimate peptide quantity of identified; 5. To assess the impact of purified lectins to Balb/c mice immune system reactions in vivo.